Proctitis is an inflammation of the rectum that causes discomfort, bleeding, and occasionally, a discharge of mucus or pus.
Inflammation - rectum; Rectal inflammation
There are many causes of proctitis, but they can be grouped in the following categories:
- Autoimmune disease
- Harmful substances
- Non-sexually transmitted infection
- Sexually transmitted disease (STD)
Proctitis caused by STD is common among those who engage in anal intercourse. STDs that can cause proctitis include gonorrhea, herpes, chlamydia, and lymphogranuloma venereum.
Non-sexually transmitted infections causing proctitis are seen less often than STD proctitis. The classical example of non-sexually transmitted infection occurs in children and is caused by the same bacteria that cause strep throat.
Autoimmune proctitis is associated with diseases such as ulcerative colitis or Crohn's disease.
Proctitis may also be caused by certain medications, radiotherapy, and inserting harmful substances into the rectum.
Risk factors include:
Exams and Tests
Successful treatment of the underlying cause usually cures the problem. Proctitis caused by infection is treated with antibiotics.
Corticosteroids or mesalamine suppositories may relieve symptoms of some patients.
The probable outcome is good with treatment.
- Anal fistula
- Recto-vaginal fistula (women)
- Severe bleeding
When to Contact a Medical Professional
Call for an appointment with your health care provider if you have symptoms of proctitis.
Safer sex behaviors may prevent the disease from being spread during sexual activity.
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Giannella RA. Infectious enteritis and proctocolitis and bacterial food poisoning. In: Feldman M, Friedman LS, Brandt LJ, eds. Sleisenger & Fordtran’s Gastrointestinal and Liver Disease. 9th ed. Philadelphia, Pa: Saunders Elsevier; 2010:chap 107.
Osterman MT, Lichtenstein GR. Ulcerative colitis. In: Feldman M, Friedman LS, Brandt LJ, eds. Sleisenger & Fordtran’s Gastrointestinal and Liver Disease. 9th ed. Philadelphia, Pa: Saunders Elsevier; 2010:chap 112.
Linda J. Vorvick, MD, Medical Director, MEDEX Northwest Division of Physician Assistant Studies, University of Washington, School of Medicine; George F. Longstreth, MD, Department of Gastroenterology, Kaiser Permanente Medical Care Program, San Diego, California. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.
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